Product Description
Chemical Name:β-Nicotinamide Mononucleotide
CAS No.:1094-61-7
EINECS NO:214-136-5
MF: C11H15N2O8P
MW: 334.22
Melting point:166 °C(dec.)
product modality:Solid
color:White to Yellow
Product properties & Features
Nicotinamide mononucleotide, also known as β-nicotinamide mononucleotide (NMN), is a synthetic substrate for coenzyme I, and NMN is also used in anti-aging research. Studies have shown that β-NMN can also regulate the secretion of insulin and affect the expression level of mRNA. β-NMN has a wide range of application prospects in the field of medical treatment. Beta-niacinamide mononucleoside Chemicalbook acid is a product of the reaction of the extracellular niacinamide phosphoribose transferase (eNAMPT) and a key NAD+ intermediate. It improves glucose tolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances liver insulin sensitivity and restores gene expression associated with oxidative stress, inflammatory response, and circadian rhythm, in part through SIRT1 activation.
Application
In mammals, β-niacinamide mononucleotides are produced by Nicotinamide (Nam) catalyzed by Nampt, a protease in vivo, followed by NAD+ catalyzed by nicotinamide mononucleotide adenosine transferase. Niacinamide mononucleotide is a direct way to supplement NAD+. It is by significantly improving the repair ability of DNA damage in cells that niacinamide mononucleotide finally realizes the effect of reversing senescence. Niacinamide mononucleotides are converted into a substance called "niacinamide adenine dinucleotide (NAD)" which is essential for energy metabolism in the body. In mice, niacinamide mononucleotides have been shown to activate a gene in the body called acetylase, which can play a role in prolonging life and treating diabetes. Studies have shown that levels of Nads, which are naturally produced by the body, decrease with age.
Storage
Storage and transportation:-20°C
